TRIGONIL TABLET

Deal The Triglycerides Easily’

Trigonil tablet is an Ayurvedic Proprietary Medicine from Vaidyaratnam Oushadhasala useful in the treatment of Hypertriglyceridaemia. The product is presented in the  form of tablet  containing  7 ingredients - Atasi, Rasona, Jathiphala, Hareethaki, Vibithaki, Amalaki and Maricha. 

Indication: Hypertriglyceridaemia

Experiential wisdom : High levels of  Triglycerides  

Dosage : 1-2 tablets  after food or as directed by the physician.

Ingredients:

Each tablet prepared out of :

Cumulative Pharmacological properties of the  formulation:

Rasa: Thiktha madhura kashaya katu

Virya: Ushna

Vipaka: Katu

Cumulative Pharmacological action of the  formulation :

Doshakarma: Tridoshahara,especially kaphahara

Dhathukarma: Medhohara

Agnikarma: Deepana,pachana

Anyakarma: Vibandhagna, hrdrogaghna, sulagna, sophagna, avaranagna.

Supportive phytoconstituents :

Fiber component consisting of d-xylose, l-galactose, l-rhamnose, d-galacturonic acid, galactose, Alpha-linolenic acid (Linum usitatissimum), Allicin, Allyl propyl disulfide,  cysteine sulfoxide, S-allyl cysteine sulfoxide (Allium sativum),  Myristic acid (Myristica fragrans), Emblicanin A , emblicanin B (Emblica officinalis) and Piperine(Piper nigrum).

Risk factors involved in hypertryglyceridemia:

Pharmacodynamics :

The mechanism of hypertriglyceridemia in the setting of obesity has been linked to insulin resistance, wherein an increased flux of adipose tissue–derived free fatty acids (FFAs) gives rise to increased rates of hepatic triglyceride synthesis and secretion of very-low-density lipoprotein (VLDL) triglycerides.

On analysing this  formula , it shows the following Pharmacological actions:

Ayurvedic point of view :

In  Hypertriglyceridaemia , medodhatvagni mandhya  play a key role for medovaha-srotodushti along with vitiation of kapha dosha.  This formulation is predominant of katu vipaka. Katu vipaka is having laghu, ruksha guna, so it acts as kaphahara.Thiktha and kashaya rasa are  acts as pitha and kaphahara. Medas is body tissue predominant in Prithvi and Ap Mahabhutas similar to Kapha Dosha. So this formulation can be given in medoroga.

Conclusion

Bibliography